HRT monographPractical HRT

2nd expanded edition by P. Kenemans, R. Barentsen and P. van de Weijer

Preface to the second, extended edition

Within the space of just one year following the publication of the first edition of Practical HRT, the need for a second edition was apparent. All 11,000 copies of the first edition had found their destination and in the meantime important publications had appeared such as the PEPI Study (on cardiovascular risk factors and combined HRT [1]) and the update of the Nurses' Health Study (on breast cancer morbidity and mortality under combined HRT [2]).

In a practical, client-oriented book like Practical HRT, the basic facts, the clinical evaluation strategies and the advice concerning the avenues of treatment and management should be entirely up-to-date. In many chapters small alterations in text and reference list reflect these necessary adjustments. In addition, the chapters on Cancer Risk (Chapter 10) and on Compliance (Chapter 22) have been rewritten and a new chapter on The Central Nervous System (Chapter 7) has been added.

We feel that this extended, second edition of PracticalHRT will serve both the individual woman and her health provider better.

Peter Kenemans, Ronald Barentsen and Peter van de Weijer
Amsterdam, May 1996

1. The writing group for the PEPI trial. Effects of estrogen or estrogen/progestin regimens on heart disease risk factors in postmenopausal women. J Am Med Assoc 1995;273:199-206.
2. Colditz GA, Hankinson SE, Hunter DJ, et al. The use of oestrogens and progestins and the risk of breast cancer in postmenopausal women. New Engl J Med 1995;332:1589-93.